Max Delbrück Center (MDC) for Molecular Medicine
The second annual course on Complex Trait Analysis of Next Generation Sequence Data will be held at the MDC in Berlin from July 4-8, 2016. The goal of the course is to teach course participants both the theory and application of methods to analyze next generation sequence (NGS) data for human complex traits. Attendees will learn how to design studies, call variants from NGS data, analysis of population- and trio- based sequence data and evaluation of variant functionality. Analyses will include performing complex trait rare variant association analysis for population and trio data. Exercises will be carried out using a variety of computer programs (GATK, IGV, Polyphen2, PSEQ, SEQPower, and Variant Association Tools (VAT)). TOPICS will be include: sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects and mixed models), rare variant association methods, estimating power and sample size for rare variant association studies, imputation of rare variants and evaluating variant functionality.
The instructors for the course are Suzanne Leal (Baylor College of Medicine) and Michael Nothnagel (University of Cologne).
For additional information, course schedule and application form please
visit the course website:
Please follow the links attached for further information.
Our second keynote address by Prof. Kingsmore's is entitled "Clinical implications of 2-day whole genome sequencing of acutely ill infants".
Directions to venue:
Please use Collins Avenue entrance to DCU. The meeting is in the Lonsdale building on the ground floor.
Campus map: https://www.dcu.ie/sites/default/files/campus_map.pdf
We had a very successful meeting and our thanks go to our keynote speaker Prof. Stephen Kingsmore, Dee Lyons/Missouri Endowed Chair in Genomic Medicine, Children’s Mercy, Kansas.
Congratulations to Caragh Stapleton on winning the Young Investigator Award for her presentation entitled "Identifying Genetic Predictors of Skin Cancer in Renal Transplant Populations".
Congratulations to Dr. Jillian Casey on winning the Best Post Doc Oral presentation entitled "When it Comes to Exomes, Expect the Unexpected".